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Pharmacokinetic model of unfractionated heparin during and after cardiopulmonary bypass in cardiac surgery
BACKGROUND: Unfractionated heparin (UFH) is widely used as a reversible anti-coagulant in cardiopulmonary bypass (CPB). However, the pharmacokinetic characteristics of UFH in CPB surgeries remain unknown because of the lack of means to directly determine plasma UFH concentrations. The aim of this st...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326208/ https://www.ncbi.nlm.nih.gov/pubmed/25638272 http://dx.doi.org/10.1186/s12967-015-0404-5 |