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Pharmacokinetic model of unfractionated heparin during and after cardiopulmonary bypass in cardiac surgery

BACKGROUND: Unfractionated heparin (UFH) is widely used as a reversible anti-coagulant in cardiopulmonary bypass (CPB). However, the pharmacokinetic characteristics of UFH in CPB surgeries remain unknown because of the lack of means to directly determine plasma UFH concentrations. The aim of this st...

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Detalles Bibliográficos
Autores principales:	Jia, Zaishen, Tian, Ganzhong, Ren, Yupeng, Sun, Zhiquan, Lu, Wei, Hou, Xiaotong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326208/ https://www.ncbi.nlm.nih.gov/pubmed/25638272 http://dx.doi.org/10.1186/s12967-015-0404-5

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