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Anaplastic Thyroid Carcinoma: A ceRNA Analysis Pointed to a Crosstalk between SOX2, TP53, and microRNA Biogenesis

It has been suggested that cancer stem cells (CSC) may play a central role in oncogenesis, especially in undifferentiated tumours. Anaplastic thyroid carcinoma (ATC) has characteristics suggestive of a tumour enriched in CSC. Previous studies suggested that the stem cell factor SOX2 has a preeminent...

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Detalles Bibliográficos
Autores principales: Arancio, Walter, Carina, Valeria, Pizzolanti, Giuseppe, Tomasello, Laura, Pitrone, Maria, Baiamonte, Concetta, Amato, Marco Calogero, Giordano, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326218/
https://www.ncbi.nlm.nih.gov/pubmed/25705224
http://dx.doi.org/10.1155/2015/439370