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The protective effect of growth hormone on Cu/Zn superoxide dismutase-mutant motor neurons
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is characterized by selective degeneration of motor neurons. The gene encoding Cu/Zn superoxide dismutase (SOD1) is responsible for 20% of familial ALS cases. Growth hormone (GH) concentrations are low in the cerebrospinal fluid of patients with ALS; h...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326297/ https://www.ncbi.nlm.nih.gov/pubmed/25655275 http://dx.doi.org/10.1186/s12868-015-0140-z |