The protective effect of growth hormone on Cu/Zn superoxide dismutase-mutant motor neurons

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is characterized by selective degeneration of motor neurons. The gene encoding Cu/Zn superoxide dismutase (SOD1) is responsible for 20% of familial ALS cases. Growth hormone (GH) concentrations are low in the cerebrospinal fluid of patients with ALS; h...

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Detalles Bibliográficos
Autores principales: Chung, Jin-Young, Kim, Hyun-Jung, Kim, Manho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326297/
https://www.ncbi.nlm.nih.gov/pubmed/25655275
http://dx.doi.org/10.1186/s12868-015-0140-z

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