Cleavage of the moaX-encoded fused molybdopterin synthase from Mycobacterium tuberculosis is necessary for activity

BACKGROUND: Molybdopterin cofactor (MoCo) biosynthesis in Mycobacterium tuberculosis is associated with a multiplicity of genes encoding several enzymes in the pathway, including the molybdopterin (MPT) synthase, a hetero tetramer comprising two MoaD and two MoaE subunits. In addition to moaD1, moaD...

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Detalles Bibliográficos
Autores principales: Narrandes, Nicole C, Machowski, Edith Erika, Mizrahi, Valerie, Kana, Bavesh D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326299/
https://www.ncbi.nlm.nih.gov/pubmed/25651977
http://dx.doi.org/10.1186/s12866-015-0355-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326299/
https://www.ncbi.nlm.nih.gov/pubmed/25651977
http://dx.doi.org/10.1186/s12866-015-0355-2

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