Cargando…

Cleavage of the moaX-encoded fused molybdopterin synthase from Mycobacterium tuberculosis is necessary for activity

BACKGROUND: Molybdopterin cofactor (MoCo) biosynthesis in Mycobacterium tuberculosis is associated with a multiplicity of genes encoding several enzymes in the pathway, including the molybdopterin (MPT) synthase, a hetero tetramer comprising two MoaD and two MoaE subunits. In addition to moaD1, moaD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Narrandes, Nicole C, Machowski, Edith Erika, Mizrahi, Valerie, Kana, Bavesh D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326299/ https://www.ncbi.nlm.nih.gov/pubmed/25651977 http://dx.doi.org/10.1186/s12866-015-0355-2

Ejemplares similares

Molybdopterin Biosynthesis: Trapping of Intermediates for the MoaA-Catalyzed Reaction Using 2′-DeoxyGTP and 2′-ChloroGTP as Substrate Analogues.
por: Mehta, Angad P., et al.
Publicado: (2014)

Complete Genome Sequence of Lopsy, a B1 Cluster Mycobacteriophage
por: Ealand, Christopher, et al.
Publicado: (2023)

Comparative genomics for mycobacterial peptidoglycan remodelling enzymes reveals extensive genetic multiplicity
por: Machowski, Edith Erika, et al.
Publicado: (2014)

Complete genome sequence of Azrael100, a V cluster mycobacteriophage
por: Machowski, Edith Erika, et al.
Publicado: (2023)

The resuscitation-promoting factors of Mycobacterium tuberculosis are required for virulence and resuscitation from dormancy but are collectively dispensable for growth in vitro
por: Kana, Bavesh D, et al.
Publicado: (2008)

Characterization of putative DD-carboxypeptidase-encoding genes in Mycobacterium smegmatis
por: Ealand, Christopher S., et al.
Publicado: (2019)

The Role of the Nucleotides in the Insertion of the bis-Molybdopterin Guanine Dinucleotide Cofactor into apo-Molybdoenzymes
por: Tiedemann, Kim, et al.
Publicado: (2022)

Open MoA: revealing the mechanism of action (MoA) based on network topology and hierarchy
por: Liao, Xinmeng, et al.
Publicado: (2023)

Noncovalent Interactions Involving Group 6 in Biological Systems: The Case of Molybdopterin and Tungstopterin Cofactors
por: Bauzá, Antonio, et al.
Publicado: (2022)

Museo de Bellas Artes Moa.
Publicado: (1982)

Magnetoresistance and robust resistivity plateau in MoAs(2)
por: Wang, Jialu, et al.
Publicado: (2017)

Characterization of the transcriptional regulator Rv3124 of Mycobacterium tuberculosis identifies it as a positive regulator of molybdopterin biosynthesis and defines the functional consequences of a non-synonymous SNP in the Mycobacterium bovis BCG orthologue
por: Mendoza Lopez, Pablo, et al.
Publicado: (2010)

Detection of differentially culturable tubercle bacteria in sputum using mycobacterial culture filtrates
por: Gordhan, Bhavna G., et al.
Publicado: (2021)

Molybdopterin biosynthesis pathway contributes to the regulation of SaeRS two-component system by ClpP in Staphylococcus aureus
por: Zhao, Na, et al.
Publicado: (2022)

Machine learning for data streams: with practical examples in MOA
por: Bifet, Albert, et al.
Publicado: (2017)

Leakage Current Sensor and Neural Network for MOA Monitoring
por: He, Tao, et al.
Publicado: (2022)

Mycobacterium smegmatis does not display functional redundancy in nitrate reductase enzymes
por: Cardoso, Nicole C., et al.
Publicado: (2021)

Highly Informative Ancient DNA ‘Snippets’ for New Zealand Moa
por: McCallum, Jonathan, et al.
Publicado: (2013)

MoaE Is Involved in Response to Oxidative Stress in Deinococcus radiodurans
por: Cai, Jianling, et al.
Publicado: (2023)

VapC Toxins from Mycobacterium tuberculosis Are Ribonucleases that Differentially Inhibit Growth and Are Neutralized by Cognate VapB Antitoxins
por: Ahidjo, Bintou Ahmadou, et al.
Publicado: (2011)

Computational analyses of mechanism of action (MoA): data, methods and integration
por: Trapotsi, Maria-Anna, et al.
Publicado: (2021)

Dissolution performance of cellulose in [A(2)im][MOA]/MIM solvents
por: Xu, Airong, et al.
Publicado: (2019)

Beyond Moco Biosynthesis―Moonlighting Roles of MoaE and MOCS2
por: Suganuma, Tamaki
Publicado: (2022)

Structural Insights into Putative Molybdenum Cofactor Biosynthesis Protein C (MoaC2) from Mycobacterium tuberculosis H37Rv
por: Srivastava, Vijay Kumar, et al.
Publicado: (2013)

Peptidoglycan compositional analysis of Mycobacterium smegmatis using high-resolution LC–MS
por: Rimal, Binayak, et al.
Publicado: (2022)

Correction: Structural Insights into Putative Molybdenum Cofactor Biosynthesis Protein C (MoaC2) from Mycobacterium tuberculosis H37Rv
por: Srivastava, Vijay Kumar, et al.
Publicado: (2013)

Is it necessary to fuse to the pelvis when correcting scoliosis in cerebral palsy?
por: Strom, Shane F, et al.
Publicado: (2022)

Complex Species Status for Extinct Moa (Aves: Dinornithiformes) from the Genus Euryapteryx
por: Huynen, Leon, et al.
Publicado: (2014)

Identification, Classification, and Growth of Moa Chicks (Aves: Dinornithiformes) from the Genus Euryapteryx
por: Huynen, Leon, et al.
Publicado: (2014)

Characterisation of a putative M23-domain containing protein in Mycobacterium tuberculosis
por: Papadopoulos, Andrea Olga, et al.
Publicado: (2021)

The role of resuscitation promoting factors in pathogenesis and reactivation of Mycobacterium tuberculosis during intra-peritoneal infection in mice
por: Biketov, Sergey, et al.
Publicado: (2007)

N–O Cleavage reactions of heterobicycloalkene-fused 2-isoxazolines
por: Nagireddy, Jaipal R, et al.
Publicado: (2014)

Which functional groups of the molybdopterin ligand should be considered when modeling the active sites of the molybdenum and tungsten cofactors? A density functional theory study
por: Ryde, Ulf, et al.
Publicado: (2009)

A Megafauna’s Microfauna: Gastrointestinal Parasites of New Zealand’s Extinct Moa (Aves: Dinornithiformes)
por: Wood, Jamie R., et al.
Publicado: (2013)

Correction: Identification, Classification, and Growth of Moa Chicks (Aves: Dinornithiformes) from the Genus Euryapteryx
Publicado: (2014)

Electronic structure and topological properties of centrosymmetric MoAs(2)/WAs(2) from first principles
por: Chen, Jia, et al.
Publicado: (2017)

Studying the antecedents and outcome of social media use by salespeople using a MOA framework
por: Guenzi, Paolo, et al.
Publicado: (2020)

Crystal structure of MOA in complex with a peptide fragment: A protease caught in flagranti
por: Manna, Dipankar, et al.
Publicado: (2020)

Characterization of ENM Dynamic Dose-Dependent MOA in Lung with Respect to Immune Cells Infiltration
por: Serra, Angela, et al.
Publicado: (2022)

Identification of moaA3 gene in patient isolates of Mycobacterium tuberculosis in Kerala, which is absent in M. tuberculosis H37Rv and H37Ra
por: Sarojini, Suma, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_u4oss9b3ghmc8era7qqo2gvjvj