High-density SNP arrays improve detection of HER2 amplification and polyploidy in breast tumors

BACKGROUND: Human epidermal growth factor receptor-2 (HER2) overexpression and gene amplification are currently established by immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH), respectively. This study investigates whether high-density single nucleotide polymorphism (SNP) arr...

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Detalles Bibliográficos
Autores principales: Hansen, Thomas v O, Vikesaa, Jonas, Buhl, Sine S, Rossing, Henrik H, Timmermans-Wielenga, Vera, Nielsen, Finn C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326399/
https://www.ncbi.nlm.nih.gov/pubmed/25655188
http://dx.doi.org/10.1186/s12885-015-1035-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326399/
https://www.ncbi.nlm.nih.gov/pubmed/25655188
http://dx.doi.org/10.1186/s12885-015-1035-1

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