Haplotypes at LBX1 Have Distinct Inheritance Patterns with Opposite Effects in Adolescent Idiopathic Scoliosis

Adolescent idiopathic scoliosis (AIS) is a clinically significant disorder with high heritability that affects 2–4% of the population. Genome-wide association studies have identified LBX1 as a strong susceptibility locus for AIS in Asian and Caucasian populations. Here we further dissect the genetic...

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Detalles Bibliográficos
Autores principales: Chettier, Rakesh, Nelson, Lesa, Ogilvie, James W., Albertsen, Hans M., Ward, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326419/
https://www.ncbi.nlm.nih.gov/pubmed/25675428
http://dx.doi.org/10.1371/journal.pone.0117708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326419/
https://www.ncbi.nlm.nih.gov/pubmed/25675428
http://dx.doi.org/10.1371/journal.pone.0117708

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