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Variant RONΔ160 of the RON receptor tyrosine kinase promotes the growth and invasion in vitro and in vivo in gastric cancer cell lines

BACKGROUND: Recepteur d’origine nantais (RON) is a receptor tyrosine kinase whose overexpression has been observed in human gastric cancers. This study aimed to determine whether overexpression of the variant RONΔ160 could induce tumorigenicity of gastric cancer cells in vitro or in vivo, and whethe...

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Detalles Bibliográficos
Autores principales: Zhou, Dong-Hui, Li, Chao, Yang, Li-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326440/
https://www.ncbi.nlm.nih.gov/pubmed/25685065
http://dx.doi.org/10.1186/s12935-015-0157-5