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SOX1 down-regulates β-catenin and reverses malignant phenotype in nasopharyngeal carcinoma
BACKGROUND: Aberrant activation of the Wnt/β-catenin signaling pathway is an important factor in the development of nasopharyngeal carcinoma (NPC). Previous studies have demonstrated that the developmental gene sex-determining region Y (SRY)-box 1 (SOX1) inhibits cervical and liver tumorigenesis by...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326525/ https://www.ncbi.nlm.nih.gov/pubmed/25427424 http://dx.doi.org/10.1186/1476-4598-13-257 |