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SOX1 down-regulates β-catenin and reverses malignant phenotype in nasopharyngeal carcinoma

BACKGROUND: Aberrant activation of the Wnt/β-catenin signaling pathway is an important factor in the development of nasopharyngeal carcinoma (NPC). Previous studies have demonstrated that the developmental gene sex-determining region Y (SRY)-box 1 (SOX1) inhibits cervical and liver tumorigenesis by...

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Detalles Bibliográficos
Autores principales:	Guan, Zhong, Zhang, Jialiang, Wang, Jing, Wang, Hefei, Zheng, Feimeng, Peng, Jieren, Xu, Yaodong, Yan, Min, Liu, Bing, Cui, Bai, Huang, Ying, Liu, Quentin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326525/ https://www.ncbi.nlm.nih.gov/pubmed/25427424 http://dx.doi.org/10.1186/1476-4598-13-257

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