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IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology

Interleukin-23 (IL-23) responsive group 3 innate lymphoid cells (ILC3s) have been implicated in immune homeostasis and pathogenesis in the adult, but little is known about their roles in the newborn. Here we show that IL-23 promotes conversion of embryonic intestinal Lin(−)IL-23R(+)Thy1(+) cells int...

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Detalles Bibliográficos
Autores principales: Chen, Lili, He, Zhengxiang, Slinger, Erik, Bongers, Gerold, Lapenda, Taciana L.S., Pacer, Michelle E., Jiao, Jingjing, Beltrao, Monique F., Soto, Alan J., Harpaz, Noam, Gordon, Ronald E., Ochando, Jordi C., Oukka, Mohamed, Iuga, Alina Cornelia, Chensue, Stephen W., Blander, Julie Magarian, Furtado, Glaucia C., Lira, Sergio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326561/
https://www.ncbi.nlm.nih.gov/pubmed/25160819
http://dx.doi.org/10.1038/mi.2014.77