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Phosphatidylethanolamine positively regulates autophagy and longevity

Autophagy is a cellular recycling program that retards ageing by efficiently eliminating damaged and potentially harmful organelles and intracellular protein aggregates. Here, we show that the abundance of phosphatidylethanolamine (PE) positively regulates autophagy. Reduction of intracellular PE le...

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Detalles Bibliográficos
Autores principales: Rockenfeller, P, Koska, M, Pietrocola, F, Minois, N, Knittelfelder, O, Sica, V, Franz, J, Carmona-Gutierrez, D, Kroemer, G, Madeo, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326582/
https://www.ncbi.nlm.nih.gov/pubmed/25571976
http://dx.doi.org/10.1038/cdd.2014.219