Cargando…

Phosphatidylethanolamine positively regulates autophagy and longevity

Autophagy is a cellular recycling program that retards ageing by efficiently eliminating damaged and potentially harmful organelles and intracellular protein aggregates. Here, we show that the abundance of phosphatidylethanolamine (PE) positively regulates autophagy. Reduction of intracellular PE le...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rockenfeller, P, Koska, M, Pietrocola, F, Minois, N, Knittelfelder, O, Sica, V, Franz, J, Carmona-Gutierrez, D, Kroemer, G, Madeo, F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326582/ https://www.ncbi.nlm.nih.gov/pubmed/25571976 http://dx.doi.org/10.1038/cdd.2014.219

Ejemplares similares

Spermidine promotes stress resistance in Drosophila melanogaster through autophagy-dependent and -independent pathways
por: Minois, N, et al.
Publicado: (2012)

Ethanolamine: A novel anti-aging agent
por: Rockenfeller, Patrick, et al.
Publicado: (2015)

Acetyl-coenzyme A: A metabolic master regulator of autophagy and longevity
por: Schroeder, Sabrina, et al.
Publicado: (2014)

Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers
por: Mariño, Guillermo, et al.
Publicado: (2014)

Spermidine Feeding Decreases Age-Related Locomotor Activity Loss and Induces Changes in Lipid Composition
por: Minois, Nadège, et al.
Publicado: (2014)

Trans-Fats Inhibit Autophagy Induced by Saturated Fatty Acids
por: Sauvat, Allan, et al.
Publicado: (2018)

Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?
por: Madeo, Frank, et al.
Publicado: (2018)

The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species
por: Carmona-Gutierrez, Didac, et al.
Publicado: (2019)

Polyamines in aging and disease
por: Minois, Nadège, et al.
Publicado: (2011)

α-Ketoglutarate inhibits autophagy
por: Baracco, Elisa Elena, et al.
Publicado: (2019)

Digesting the crisis: autophagy and coronaviruses
por: Carmona-Gutierrez, Didac, et al.
Publicado: (2020)

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy
por: Morselli, E, et al.
Publicado: (2010)

Acyl-CoA-binding protein (ACBP): the elusive ‘hunger factor' linking autophagy to food intake
por: Pedro, José Manuel Bravo-San, et al.
Publicado: (2019)

ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer
por: Quazi, Faraz, et al.
Publicado: (2012)

Stress-related hormone reduces autophagy through the regulation of phosphatidylethanolamine in breast cancer cells
por: Zhu, Zhen, et al.
Publicado: (2021)

3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB
por: Chen, Guo, et al.
Publicado: (2019)

The metabolomic signature of extreme longevity: naked mole rats versus mice
por: Viltard, Mélanie, et al.
Publicado: (2019)

SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production
por: Mitroi, Daniel N., et al.
Publicado: (2017)

4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects
por: Zimmermann, Andreas, et al.
Publicado: (2019)

A histone point mutation that switches on autophagy
por: Eisenberg, Tobias, et al.
Publicado: (2014)

Porin 1 Modulates Autophagy in Yeast
por: Broeskamp, Filomena, et al.
Publicado: (2021)

One cell, one love: a journal for microbial research
por: Carmona-Gutierrez, Didac, et al.
Publicado: (2014)

Diacylglycerol triggers Rim101 pathway–dependent necrosis in yeast: a model for lipotoxicity
por: Rockenfeller, Patrick, et al.
Publicado: (2017)

Aspirin induces autophagy via inhibition of the acetyltransferase EP300
por: Castoldi, Francesca, et al.
Publicado: (2018)

Autophagy and Longevity
por: Nakamura, Shuhei, et al.
Publicado: (2018)

Spermidine delays aging in humans
por: Madeo, Frank, et al.
Publicado: (2018)

The Influence of pH on Phosphatidylethanolamine Monolayer at the Air/Aqueous Solution Interface
por: Petelska, Aneta Dorota, et al.
Publicado: (2012)

Neo1 and phosphatidylethanolamine contribute to vacuole membrane fusion in Saccharomyces cerevisiae
por: Wu, Yuantai, et al.
Publicado: (2016)

Systemic autophagy in the therapeutic response to anthracycline-based chemotherapy
por: Castoldi, Francesca, et al.
Publicado: (2018)

Ethanolamine and Phosphatidylethanolamine: Partners in Health and Disease
por: Patel, Dhaval, et al.
Publicado: (2017)

Phosphatidylethanolamine dynamics are required for osteoclast fusion
por: Irie, Atsushi, et al.
Publicado: (2017)

Autophagy: one more Nobel Prize for yeast
por: Zimmermann, Andreas, et al.
Publicado: (2016)

DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression
por: Aldrovandi, Maceler, et al.
Publicado: (2017)

Multifaceted membrane interactions of human Atg3 promote LC3-phosphatidylethanolamine conjugation during autophagy
por: Ye, Yansheng, et al.
Publicado: (2023)

SMAC/Diablo controls proliferation of cancer cells by regulating phosphatidylethanolamine synthesis
por: Pandey, Swaroop Kumar, et al.
Publicado: (2021)

Schisandra lignans ameliorate nonalcoholic steatohepatitis by regulating aberrant metabolism of phosphatidylethanolamines
por: Xue, Lijuan, et al.
Publicado: (2023)

Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes
por: Dias, Catarina, et al.
Publicado: (2018)

Autophagy and longevity: Evolutionary hints from hyper-longevous mammals
por: Locatelli, Andrea G., et al.
Publicado: (2022)

A calcium-dependent acyltransferase that produces N-acyl phosphatidylethanolamines
por: Ogura, Yuji, et al.
Publicado: (2016)

WIPI-Mediated Autophagy and Longevity
por: Grimmel, Mona, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_131474kk3b7dh1h6js9ol2ca20