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Transcriptome Sequencing and Genome-wide Association Analyses Reveal Lysosomal Function and Actin Cytoskeleton Remodeling in Schizophrenia and Bipolar Disorder

Schizophrenia (SCZ) and bipolar disorder (BPD) are severe mental disorders with high heritability. Clinicians have long noticed the similarities of clinic symptoms between these disorders. In recent years, accumulating evidence indicates some shared genetic liabilities. However, what is shared remai...

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Detalles Bibliográficos
Autores principales: Zhao, Zhongming, Xu, Jiabao, Chen, Jingchun, Kim, Sanghyeon, Reimers, Mark, Bacanu, Silviu-Alin, Yu, Hui, Liu, Chunyu, Sun, Jingchun, Wang, Quan, Jia, Peilin, Xu, Fengping, Zhang, Yong, Kendler, Kenneth S., Peng, Zhiyu, Chen, Xiangning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326626/
https://www.ncbi.nlm.nih.gov/pubmed/25113377
http://dx.doi.org/10.1038/mp.2014.82