A novel inhibitor of the insulin/IGF signaling pathway protects from age-onset, neurodegeneration-linked proteotoxicity

Aging manipulation is an emerging strategy aimed to postpone the manifestation of late-onset neurodegenerative disorders such as Alzheimer’s (AD) and Huntington’s diseases (HD) and to slow their progression once emerged. Reducing the activity of the insulin/IGF signaling cascade (IIS), a prominent a...

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Detalles Bibliográficos
Autores principales: El-Ami, Tayir, Moll, Lorna, Carvalhal Marques, Filipa, Volovik, Yuli, Reuveni, Hadas, Cohen, Ehud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326862/
https://www.ncbi.nlm.nih.gov/pubmed/24261972
http://dx.doi.org/10.1111/acel.12171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326862/
https://www.ncbi.nlm.nih.gov/pubmed/24261972
http://dx.doi.org/10.1111/acel.12171

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