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The aging signature: a hallmark of induced pluripotent stem cells?

The discovery that somatic cells can be induced into a pluripotent state by the expression of reprogramming factors has enormous potential for therapeutics and human disease modeling. With regard to aging and rejuvenation, the reprogramming process resets an aged, somatic cell to a more youthful sta...

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Detalles Bibliográficos
Autores principales: Rohani, Leili, Johnson, Adiv A, Arnold, Antje, Stolzing, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326871/
https://www.ncbi.nlm.nih.gov/pubmed/24256351
http://dx.doi.org/10.1111/acel.12182