Up-regulation of β-amyloidogenesis in neuron-like human cells by both 24- and 27-hydroxycholesterol: protective effect of N-acetyl-cysteine

An abnormal accumulation of cholesterol oxidation products in the brain of patients with Alzheimer’s disease (AD) would further link an impaired cholesterol metabolism in the pathogenesis of the disease. The first evidence stemming from the content of oxysterols in autopsy samples from AD and normal...

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Detalles Bibliográficos
Autores principales: Gamba, Paola, Guglielmotto, Michela, Testa, Gabriella, Monteleone, Debora, Zerbinati, Chiara, Gargiulo, Simona, Biasi, Fiorella, Iuliano, Luigi, Giaccone, Giorgio, Mauro, Alessandro, Poli, Giuseppe, Tamagno, Elena, Leonarduzzi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326893/
https://www.ncbi.nlm.nih.gov/pubmed/24612036
http://dx.doi.org/10.1111/acel.12206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326893/
https://www.ncbi.nlm.nih.gov/pubmed/24612036
http://dx.doi.org/10.1111/acel.12206

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