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Superoxide signaling in perivascular adipose tissue promotes age-related artery stiffness

We tested the hypothesis that superoxide signaling within aortic perivascular adipose tissue (PVAT) contributes to large elastic artery stiffening in old mice. Young (4–6 months), old (26–28 months), and old treated with 4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl (TEMPOL), a superoxide scavenger...

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Detalles Bibliográficos
Autores principales: Fleenor, Bradley S, Eng, Jason S, Sindler, Amy L, Pham, Bryant T, Kloor, Jackson D, Seals, Douglas R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326900/
https://www.ncbi.nlm.nih.gov/pubmed/24341314
http://dx.doi.org/10.1111/acel.12196