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Superoxide signaling in perivascular adipose tissue promotes age-related artery stiffness
We tested the hypothesis that superoxide signaling within aortic perivascular adipose tissue (PVAT) contributes to large elastic artery stiffening in old mice. Young (4–6 months), old (26–28 months), and old treated with 4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl (TEMPOL), a superoxide scavenger...
Autores principales: | Fleenor, Bradley S, Eng, Jason S, Sindler, Amy L, Pham, Bryant T, Kloor, Jackson D, Seals, Douglas R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326900/ https://www.ncbi.nlm.nih.gov/pubmed/24341314 http://dx.doi.org/10.1111/acel.12196 |
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