Granzyme B mediates both direct and indirect cleavage of extracellular matrix in skin after chronic low-dose ultraviolet light irradiation

Extracellular matrix (ECM) degradation is a hallmark of many chronic inflammatory diseases that can lead to a loss of function, aging, and disease progression. Ultraviolet light (UV) irradiation from the sun is widely considered as the major cause of visible human skin aging, causing increased infla...

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Detalles Bibliográficos
Autores principales: Parkinson, Leigh G, Toro, Ana, Zhao, Hongyan, Brown, Keddie, Tebbutt, Scott J, Granville, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326907/
https://www.ncbi.nlm.nih.gov/pubmed/25495009
http://dx.doi.org/10.1111/acel.12298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326907/
https://www.ncbi.nlm.nih.gov/pubmed/25495009
http://dx.doi.org/10.1111/acel.12298

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