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Hypoxia disrupts proteostasis in Caenorhabditis elegans
Oxygen is fundamentally important for cell metabolism, and as a consequence, O(2) deprivation (hypoxia) can impair many essential physiological processes. Here, we show that an active response to hypoxia disrupts cellular proteostasis – the coordination of protein synthesis, quality control, and deg...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326909/ https://www.ncbi.nlm.nih.gov/pubmed/25510338 http://dx.doi.org/10.1111/acel.12301 |