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Caveolae control the anti-inflammatory phenotype of senescent endothelial cells

Senescent endothelial cells (EC) have been identified in cardiovascular disease, in angiogenic tumour associated vessels and in aged individuals. We have previously identified a novel anti-inflammatory senescent phenotype of EC. We show here that caveolae are critical in the induction of this anti-i...

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Detalles Bibliográficos
Autores principales: Powter, Elizabeth E, Coleman, Paul R, Tran, Mai H, Lay, Angelina J, Bertolino, Patrick, Parton, Robert G, Vadas, Mathew A, Gamble, Jennifer R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326911/
https://www.ncbi.nlm.nih.gov/pubmed/25407919
http://dx.doi.org/10.1111/acel.12270