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ATF4 activity: a common feature shared by many kinds of slow-aging mice

ATF4, a DNA-binding factor that modulates responses to amino acid availability and ribosomal function, has been shown to be altered in both liver and fibroblasts from two strains of long-lived mice, i.e. Snell dwarf and PAPP-A knockout mice. New data now show elevated ATF4 levels, and elevation of A...

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Detalles Bibliográficos
Autores principales: Li, Weiquan, Li, Xinna, Miller, Richard A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326926/
https://www.ncbi.nlm.nih.gov/pubmed/25156122
http://dx.doi.org/10.1111/acel.12264