Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow aging

In addition to their extended lifespans, slow-aging growth hormone receptor/binding protein gene-disrupted (knockout) (GHR-KO) mice are hypoinsulinemic and highly sensitive to the action of insulin. It has been proposed that this insulin sensitivity is important for their longevity and increased hea...

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Detalles Bibliográficos
Autores principales: Arum, Oge, Boparai, Ravneet K, Saleh, Jamal K, Wang, Feiya, Dirks, Angela L, Turner, Jeremy G, Kopchick, John J, Liu, Jun-Li, Khardori, Romesh K, Bartke, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326932/
https://www.ncbi.nlm.nih.gov/pubmed/25244225
http://dx.doi.org/10.1111/acel.12262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326932/
https://www.ncbi.nlm.nih.gov/pubmed/25244225
http://dx.doi.org/10.1111/acel.12262

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