Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow aging

In addition to their extended lifespans, slow-aging growth hormone receptor/binding protein gene-disrupted (knockout) (GHR-KO) mice are hypoinsulinemic and highly sensitive to the action of insulin. It has been proposed that this insulin sensitivity is important for their longevity and increased hea...

Descripción completa

Detalles Bibliográficos
Autores principales: Arum, Oge, Boparai, Ravneet K, Saleh, Jamal K, Wang, Feiya, Dirks, Angela L, Turner, Jeremy G, Kopchick, John J, Liu, Jun-Li, Khardori, Romesh K, Bartke, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326932/
https://www.ncbi.nlm.nih.gov/pubmed/25244225
http://dx.doi.org/10.1111/acel.12262

Ejemplares similares

Ejemplares similares