Weekly administration of rapamycin improves survival and biomarkers in obese male mice on high-fat diet

Recent discoveries have revealed the key role of mTOR (target of rapamycin) in aging. Furthermore, rapamycin extends lifespan in mice, especially in female mice. Here, we treated obese male mice on high-fat diet with rapamycin given intermittently: either weekly (once a week) or alternating bi-weekl...

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Detalles Bibliográficos
Autores principales: Leontieva, Olga V, Paszkiewicz, Geraldine M, Blagosklonny, Mikhail V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326934/
https://www.ncbi.nlm.nih.gov/pubmed/24655348
http://dx.doi.org/10.1111/acel.12211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326934/
https://www.ncbi.nlm.nih.gov/pubmed/24655348
http://dx.doi.org/10.1111/acel.12211

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