Large-scale analysis reveals a functional single-nucleotide polymorphism in the 5′-flanking region of PRDM16 gene associated with lean body mass

Genetic factors are important for the development of sarcopenia, a geriatric disorder characterized by low lean body mass. The aim of this study was to search for novel genes that regulate lean body mass in humans. We performed a large-scale search for 250K single-nucleotide polymorphisms (SNPs) ass...

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Detalles Bibliográficos
Autores principales: Urano, Tomohiko, Shiraki, Masataka, Sasaki, Noriko, Ouchi, Yasuyoshi, Inoue, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326941/
https://www.ncbi.nlm.nih.gov/pubmed/24863034
http://dx.doi.org/10.1111/acel.12228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326941/
https://www.ncbi.nlm.nih.gov/pubmed/24863034
http://dx.doi.org/10.1111/acel.12228

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