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Aggravation of Alzheimer’s disease due to the COX-2-mediated reciprocal regulation of IL-1β and Aβ between glial and neuron cells

Alzheimer’s disease (AD) is the most common form of dementia and displays the characteristics of chronic neurodegenerative disorders; amyloid plaques (AP) that contain amyloid β-protein (Aβ) accumulate in AD, which is also characterized by tau phosphorylation. Epidemiological evidence has demonstrat...

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Detalles Bibliográficos
Autores principales: Wang, Pu, Guan, Pei-Pei, Wang, Tao, Yu, Xin, Guo, Jian-Jun, Wang, Zhan-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326948/
https://www.ncbi.nlm.nih.gov/pubmed/24621265
http://dx.doi.org/10.1111/acel.12209