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Gene profiling reveals association between altered Wnt signaling and loss of T-cell potential with age in human hematopoietic stem cells
Functional decline of the hematopoietic system occurs during aging and contributes to clinical consequences, including reduced competence of adaptive immunity and increased incidence of myeloid diseases. This has been linked to aging of the hematopoietic stem cell (HSC) compartment and has implicati...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326953/ https://www.ncbi.nlm.nih.gov/pubmed/24889652 http://dx.doi.org/10.1111/acel.12229 |