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Gene profiling reveals association between altered Wnt signaling and loss of T-cell potential with age in human hematopoietic stem cells

Functional decline of the hematopoietic system occurs during aging and contributes to clinical consequences, including reduced competence of adaptive immunity and increased incidence of myeloid diseases. This has been linked to aging of the hematopoietic stem cell (HSC) compartment and has implicati...

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Detalles Bibliográficos
Autores principales:	Khoo, Melissa L M, Carlin, Stephen M, Lutherborrow, Mark A, Jayaswal, Vivek, Ma, David D F, Moore, John J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326953/ https://www.ncbi.nlm.nih.gov/pubmed/24889652 http://dx.doi.org/10.1111/acel.12229

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