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TIR-domain-containing adapter-inducing interferon-β (TRIF) regulates Th17-mediated intestinal immunopathology in colitis

Gastrointestinal mucosa reserves abundant Th17 cells where host response to commensal bacteria maintains Th17-cell generation. Although functional heterogeneity and dynamic plasticity of Th17 cells appear to be involved in chronic inflammatory disorders, how their plasticity is regulated in intestin...

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Detalles Bibliográficos
Autores principales: Kanagavelu, S, Flores, C, Termini, J M, Riveron, R, Romero, L, Chung, K, Ruiz, J, Hyun, J, Yuan, X, Dagvadorj, J, Fukata, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326974/
https://www.ncbi.nlm.nih.gov/pubmed/25073675
http://dx.doi.org/10.1038/mi.2014.67