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From two competing oscillators to one coupled-clock pacemaker cell system

At the beginning of this century, debates regarding “what are the main control mechanisms that ignite the action potential (AP) in heart pacemaker cells” dominated the electrophysiology field. The original theory which prevailed for over 50 years had advocated that the ensemble of surface membrane i...

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Detalles Bibliográficos
Autores principales: Yaniv, Yael, Lakatta, Edward G., Maltsev, Victor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327306/
https://www.ncbi.nlm.nih.gov/pubmed/25741284
http://dx.doi.org/10.3389/fphys.2015.00028