Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor

Integrating signals from multiple receptors allows cells to interpret the physiological context in which a signal is received. Here we describe a mechanism for receptor crosstalk in which receptor-induced increases in actin dynamics lower the threshold for signalling by another receptor. We show tha...

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Detalles Bibliográficos
Autores principales: Freeman, Spencer A., Jaumouillé, Valentin, Choi, Kate, Hsu, Brian E., Wong, Harikesh S., Abraham, Libin, Graves, Marcia L., Coombs, Daniel, Roskelley, Calvin D., Das, Raibatak, Grinstein, Sergio, Gold, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327415/
https://www.ncbi.nlm.nih.gov/pubmed/25644899
http://dx.doi.org/10.1038/ncomms7168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327415/
https://www.ncbi.nlm.nih.gov/pubmed/25644899
http://dx.doi.org/10.1038/ncomms7168

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