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Effects of statins on T(H)1 modulating cytokines in human subjects

Background. Activation of the innate immune system by cholesterol accelerates atherosclerosis. High levels or modified forms of cholesterol stimulate release of the inflammatory cytokines IL-12 and IL-18 that synergistically stimulate T lymphocytes to produce the atherogenic cytokine interferon-γ. W...

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Detalles Bibliográficos
Autores principales: Cimato, Thomas R., Palka, Beth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327442/
https://www.ncbi.nlm.nih.gov/pubmed/25699211
http://dx.doi.org/10.7717/peerj.764