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An ESCRT module is required for neuron pruning

Neural circuits are refined by both functional and structural changes. Structural remodeling by large-scale pruning occurs where relatively long neuronal branches are cut away from their parent neuron and removed by local degeneration. Until now, the molecular mechanisms executing such branch severi...

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Detalles Bibliográficos
Autores principales: Loncle, Nicolas, Agromayor, Monica, Martin-Serrano, Juan, Williams, Darren W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327575/
https://www.ncbi.nlm.nih.gov/pubmed/25676218
http://dx.doi.org/10.1038/srep08461