GDNF-based therapies, GDNF-producing interneurons, and trophic support of the dopaminergic nigrostriatal pathway. Implications for Parkinson’s disease

The glial cell line-derived neurotrophic factor (GDNF) is a well-established trophic agent for dopaminergic (DA) neurons in vitro and in vivo. GDNF is necessary for maintenance of neuronal morphological and neurochemical phenotype and protects DA neurons from toxic damage. Numerous studies on animal...

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Detalles Bibliográficos
Autores principales: d’Anglemont de Tassigny, Xavier, Pascual, Alberto, López-Barneo, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327623/
https://www.ncbi.nlm.nih.gov/pubmed/25762899
http://dx.doi.org/10.3389/fnana.2015.00010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327623/
https://www.ncbi.nlm.nih.gov/pubmed/25762899
http://dx.doi.org/10.3389/fnana.2015.00010

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