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Host response during Yersinia pestis infection of human bronchial epithelial cells involves negative regulation of autophagy and suggests a modulation of survival-related and cellular growth pathways

Yersinia pestis (Yp) causes the re-emerging disease plague, and is classified by the CDC and NIAID as a highest priority (Category A) pathogen. Currently, there is no approved human vaccine available and advances in early diagnostics and effective therapeutics are urgently needed. A deep understandi...

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Detalles Bibliográficos
Autores principales: Alem, Farhang, Yao, Kuan, Lane, Douglas, Calvert, Valerie, Petricoin, Emanuel F., Kramer, Liana, Hale, Martha L., Bavari, Sina, Panchal, Rekha G., Hakami, Ramin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327736/
https://www.ncbi.nlm.nih.gov/pubmed/25762983
http://dx.doi.org/10.3389/fmicb.2015.00050