Cargando…

Effects of 5-azacytidine on natural killer cell activating receptor expression in patients with refractory anemia with excess of blasts

Epigenetic drugs modify DNA methylation and are used in refractory anemia with excess of blasts (RAEB). These drugs may reactivate anti-oncogene expression and restore a normal phenotype instead of inducing antitumor toxicity, although they also have immunosuppressive effects on T-lymphocytes [1] In...

Descripción completa

Detalles Bibliográficos
Autores principales: Costello, Régis T., Leclercq, Amélie, Treut, Thérèse Le, Sanchez, Carole, Mercier, Delphine, Sébahoun, Gérard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327760/
https://www.ncbi.nlm.nih.gov/pubmed/25709892
http://dx.doi.org/10.1016/j.lrr.2014.09.004