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Effects of 5-azacytidine on natural killer cell activating receptor expression in patients with refractory anemia with excess of blasts
Epigenetic drugs modify DNA methylation and are used in refractory anemia with excess of blasts (RAEB). These drugs may reactivate anti-oncogene expression and restore a normal phenotype instead of inducing antitumor toxicity, although they also have immunosuppressive effects on T-lymphocytes [1] In...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327760/ https://www.ncbi.nlm.nih.gov/pubmed/25709892 http://dx.doi.org/10.1016/j.lrr.2014.09.004 |