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Spatially restricted Hedgehog signaling regulates HGF-induced branching of the adult prostate

Branching morphogenesis is thought to be governed by epithelial-stromal interactions, but the mechanisms underlying specification of branch location remain largely unknown. Prompted by the striking absence of Hedgehog (Hh) response at the sites of nascent buds in regenerating tubules of the adult pr...

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Detalles Bibliográficos
Autores principales: Lim, Agnes, Shin, Kunyoo, Zhao, Chen, Kawano, Sally, Beachy, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327780/
https://www.ncbi.nlm.nih.gov/pubmed/25362352
http://dx.doi.org/10.1038/ncb3057