Liraglutide attenuates high glucose-induced abnormal cell migration, proliferation, and apoptosis of vascular smooth muscle cells by activating the GLP-1 receptor, and inhibiting ERK1/2 and PI3K/Akt signaling pathways

BACKGROUND: As a new anti-diabetic medicine, Liraglutide (LIRA), one of GLP-1 analogues, has been found to have an anti-atherosclerotic effect. Since vascular smooth muscle cells (VSMCs) play pivotal roles in the occurrence of diabetic atherosclerosis, it is important to investigate the role of LIRA...

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Detalles Bibliográficos
Autores principales: Shi, Lili, Ji, Ye, Jiang, Xiaoyan, Zhou, Lihong, Xu, Ying, Li, Yanbo, Jiang, Wei, Meng, Ping, Liu, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327797/
https://www.ncbi.nlm.nih.gov/pubmed/25855361
http://dx.doi.org/10.1186/s12933-015-0177-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327797/
https://www.ncbi.nlm.nih.gov/pubmed/25855361
http://dx.doi.org/10.1186/s12933-015-0177-4

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