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Interference with protease-activated receptor 1 does not reduce damage to subventricular zone cells of immature rodent brain following exposure to blood or blood plasma

BACKGROUND: Prior work showed that whole blood, plasma, and serum injections are damaging to the neonatal rodent brain in a model of intracerebral/periventricular hemorrhage. Thrombin alone is also damaging. In adult animal models of hemorrhagic stroke, the protease-activated (thrombin) receptor PAR...

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Detalles Bibliográficos
Autores principales: Mao, Xiaoyan, Del Bigio, Marc R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327806/
https://www.ncbi.nlm.nih.gov/pubmed/25649264
http://dx.doi.org/10.1186/s12952-014-0022-4