Cascade N-Alkylation/Hemiacetalization for Facile Construction of the Spiroketal Skeleton of Acortatarin Alkaloids with Therapeutic Potentiality in Diabetic Nephropathy

The concise building of the spiroketal core of acortatarin-type alkaloids as potential therapeutic agents in diabetic nephropathy was established in four steps, through a tandem N-alkylation/hemiacetalization between pyrrole units and the corresponding halo alcohols generated by convenient halomethy...

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Detalles Bibliográficos
Autores principales: Cao, Pei, Li, Zhen-Jie, Sun, Wen-Wu, Malhotra, Shashwat, Ma, Yuan-Liang, Wu, Bin, Parmar, Virinder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327998/
https://www.ncbi.nlm.nih.gov/pubmed/25511450
http://dx.doi.org/10.1007/s13659-014-0049-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327998/
https://www.ncbi.nlm.nih.gov/pubmed/25511450
http://dx.doi.org/10.1007/s13659-014-0049-8

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