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Amplification of pico-scale DNA mediated by bacterial carrier DNA for small-cell-number transcription factor ChIP-seq

BACKGROUND: Chromatin-Immunoprecipitation coupled with deep sequencing (ChIP-seq) is used to map transcription factor occupancy and generate epigenetic profiles genome-wide. The requirement of nano-scale ChIP DNA for generation of sequencing libraries has impeded ChIP-seq on in vivo tissues of low c...

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Detalles Bibliográficos
Autores principales: Jakobsen, Janus S, Bagger, Frederik O, Hasemann, Marie S, Schuster, Mikkel B, Frank, Anne-Katrine, Waage, Johannes, Vitting-Seerup, Kristoffer, Porse, Bo T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4328043/
https://www.ncbi.nlm.nih.gov/pubmed/25652644
http://dx.doi.org/10.1186/s12864-014-1195-4