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Proconvulsive effect of hydrochlorothiazide in an in vitro rat seizure model

OBJECTIVE(S): Protective effects of diuretics, particularly of hydrochlorothiazide (HCT), for the development of epilepsy have been described in vivo. However, its mechanism of action is unknown. MATERIALS AND METHODS: Extracellular field potentials were recorded from the CA1- and CA3-subfields of t...

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Detalles Bibliográficos
Autores principales: Kellinghaus, Christoph, Gorji, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4328094/
https://www.ncbi.nlm.nih.gov/pubmed/25691927