Cargando…

Differences in growth promotion, drug response and intracellular protein trafficking of FLT3 mutants

OBJECTIVE(S): Mutant forms FMS-like tyrosine kinase-3 (FLT3), are reported in 25% of childhood acute lymphoid leukemia (ALL) and 30% of acute myeloid leukemia (AML) patients. In this study, drug response, growth promoting, and protein trafficking of FLT3 wild-type was compared with two active mutant...

Descripción completa

Detalles Bibliográficos
Autores principales: Mashkani, Baratali, Griffith, Renate, Ashman, Leonie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4328095/
https://www.ncbi.nlm.nih.gov/pubmed/25691928