Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration

Physiologically, the retinal pigment epithelium (RPE) expresses immunosuppressive signals such as FAS ligand (FASL), which prevents the accumulation of leukocytes in the subretinal space. Age-related macular degeneration (AMD) is associated with a breakdown of the subretinal immunosuppressive enviro...

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Detalles Bibliográficos
Autores principales: Levy, Olivier, Calippe, Bertrand, Lavalette, Sophie, Hu, Shulong J, Raoul, William, Dominguez, Elisa, Housset, Michael, Paques, Michel, Sahel, José-Alain, Bemelmans, Alexis-Pierre, Combadiere, Christophe, Guillonneau, Xavier, Sennlaub, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4328649/
https://www.ncbi.nlm.nih.gov/pubmed/25604058
http://dx.doi.org/10.15252/emmm.201404524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4328649/
https://www.ncbi.nlm.nih.gov/pubmed/25604058
http://dx.doi.org/10.15252/emmm.201404524

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