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Noncoding RNA blockade of autophagy is therapeutic in medullary thyroid cancer

Micro-RNAs are dysregulated in medullary thyroid carcinoma (MTC) and preliminary studies have shown that miRNAs may enact a therapeutic effect through changes in autophagic flux. Our aim was to study the in vitro effect of miR-9-3p on MTC cell viability, autophagy and to investigate the mRNA autopha...

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Detalles Bibliográficos
Autores principales: Gundara, Justin S, Zhao, JingTing, Gill, Anthony J, Lee, James C, Delbridge, Leigh, Robinson, Bruce G, McLean, Catriona, Serpell, Jonathan, Sidhu, Stan B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329002/
https://www.ncbi.nlm.nih.gov/pubmed/25487826
http://dx.doi.org/10.1002/cam4.355