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Knockdown of platinum-induced growth differentiation factor 15 abrogates p27-mediated tumor growth delay in the chemoresistant ovarian cancer model A2780cis

Molecular mechanisms underlying the development of resistance to platinum-based treatment in patients with ovarian cancer remain poorly understood. This is mainly due to the lack of appropriate in vivo models allowing the identification of resistance-related factors. In this study, we used human who...

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Detalles Bibliográficos
Autores principales: Meier, Julia C, Haendler, Bernard, Seidel, Henrik, Groth, Philip, Adams, Robert, Ziegelbauer, Karl, Kreft, Bertolt, Beckmann, Georg, Sommer, Anette, Kopitz, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329009/
https://www.ncbi.nlm.nih.gov/pubmed/25490861
http://dx.doi.org/10.1002/cam4.354